Publications
Preprint
N Chang, J Wells, A Wang, P Schofield, Y Huang, V Truong, M Simoes-Costa, C Feschotte Gag proteins encoded by endogenous retroviruses are required for zebrafish development (preprint) 2024
M Singh, S Leddy, LP Iniguez, M Bendall, D Nixon, C Feschotte Transposable elements may enhance antiviral resistance in HIV-1 elite controllers bioRxiv (preprint) 2023
A Du, J Chobirko, X Zhuo, C Feschotte, T Wang Regulatory transposable elements in the encyclopedia of DNA elements bioRxiv (preprint) 2023
M Stitzer, M Khaipho-Burch, A Hudson, B Song, JA Valdez-Franco, G Ramstein, C Feschotte, E Buckler Transposable element abundance subtly contributes to lower fitness in maize. bioRxiv (preprint) 2023
2024
J Xu, S Erlendsson, M Singh, M Regier, I Ibiricu, GS Day, AL Piquet,... PNMA2 forms non-enveloped virus-like capsids that trigger paraneoplastic neurological syndrome Cell, 187: 831-845, Jan 31, 2024
2023
S Srivastav, C Feschotte, A Clark Rapid evolution of piRNA clusters in the Drosophila melanogaster ovary. Genome Research, (in press) 2023
S Namasivayam, C Sun, AB Bah, J Oberstaller, E Pierre-Louis, RD Etheridge, C Feschotte, EJ Pritham, JC Kissinger Massive invasion of organellar DNA drives nuclear genome evolution in Toxoplasma. PNAS, 120(45): e2308569120, Nov 7, 2023
D Lyons, P Kumar, N Roan, P Defechereux, C Feschotte,… HIV-1 Remission: Accelerating the Path to Permanent HIV-1 Silencing, Viruses, 15(11): 2171, Oct 28, 2023
C Feschotte Transposable elements: McClintock’s legacy revisited. Nature Reviews Genetics, 24(11): 797-800, Sept 18, 2023
JN Wells, NC Chang, J McCormick, C Coleman, N Ramos, B Jin, C Feschotte Transposable elements drive the evolution of metazoan zinc finger genes. Genome Research, 33: 1325-1339, Aug 2023
L Gozashti, C Feschotte, HE Hoekstra Transposable element interactions shape the ecology of the deer mouse genome. Molecular Biology and Evolution 40 (4) msad069, Mar 22, 2023
Y Zhou, Y Liu, S Gupta, MI Paramo, Y Hou, C Mao, Y Luo, J Judd, et al. A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets. Nature Biotechnology, 41 (1) 128-139, January 4, 2023
2022
K Angileri, N Bagia, C Feschotte Transposon control as a checkpoint for tissue regeneration. Development, 149(22) dev 191957, Nov 15, 2022
JA Frank, M Singh, HB Cullen, RA Kirou, M Benkaddour-Boumzaouad, JL Cortes, J Garcia-Perez, CB Coyne, C Feschotte Evolution and antiviral activity of a human protein of retroviral origin. Science 378, (6618), 422-428, Oct 27, 2022
R Fueyo, J Judd, C Feschotte, J Wysocka. Roles of transposable elements in the regulation of mammalian transcription. Nature Reviews Molecular Cell Biology, 1-17, Feb 28, 2022.
T Carter, M Singh, G Dumbovic, JD Chobirko, JL Rinn, C Feschotte. Mosaic cis-regulatory evolution drives transcriptional partitioning of HERVH endogenous retrovirus in the human embryo. eLife 11, e76257, Feb 18, 2022.
M Kanke, MMK Ng, S Connelly, M Singh, M Schaner, MT Shanahan, et al. Single-cell analysis reveals unexpected cellular changes and transposon expression signatures in the colonic epithelium of treatment-naïve adult Crohn’s disease patients. Cellular and Molecular Gastroenterology and Hepatology, 13 (6), 1717-1740, Feb 12, 2022.
NC Chang, Q Rovira, JN Wells, C Feschotte, JM Vaquerizas. Zebrafish transposable elements show extensive diversification in age, genomic distribution, and developmental expression. Genome Research, 32 (7), gr. 275655.121, 1408-1423, Jan 5, 2022.
2021
JL Marston, M Greenig, M Singh, ML Bendall, RRR Duarte, C Feschotte, et al. SARS-CoV-2 infection mediates differential expression of human endogenous retroviruses and long interspersed nuclear elements. JCI insight 6 (24), Dec 22, 2021.
J Judd, H Sanderson, C Feschotte. Evolution of mouse circadian enhancers from transposable elements. Genome Biology 22 (1), 1-26, Jun 29, 2021.
RL Cosby, J Judd, R Zhang, A Zhong, N Garry, EJ Pritham, C Feschotte. Recurrent evolution of vertebrate transcription factors by transposase capture. Science 371 (6531), eabc6405, Feb 19, 2021.
2020
JN Wells, C Feschotte. A field guide to eukaryotic transposable elements. Annual Review of Genetics 54, 539-561, Nov 11, 2020.
C Goubert, NA Zevallos, C Feschotte. Correction to ‘Contribution of unfixed transposable element insertions to human regulatory variation’. Philosophical Transactions of the Royal Society B 375 (1811), 20200084, Nov 9, 2020.
M Singh, H Cai, M Bunse, C Feschotte, Z Izsvák. Human endogenous retrovirus K rec forms a regulatory loop with MITF that opposes the progression of melanoma to an invasive stage. Viruses 12 (11), 1303, Nov 13, 2020.
M Singh, V Bansal, C Feschotte. A single-cell RNA expression map of human coronavirus entry factors. Cell Reports 32 (12), Sept 9, 2020.
JM Flynn, R Hubley, C Goubert, J Rosen, AG Clark, C Feschotte, AF Smit. RepeatModeler2 for automated genomic discovery of transposable element families. Proceedings of the National Academy of Sciences 117 (17), 9451-9457, April 28, 2020.
C Goubert, J Thomas, LM Payer, JM Kidd, J Feusier, WS Watkins, et al. TypeTE: a tool to genotype mobile element insertions from whole genome resequencing data. Nucleic Acids Research 48 (6), e36-e36, April 6, 2020
S Erlendsson, DR Morado, HB Cullen, C Feschotte, JD Shepherd, et al. Structures of virus-like capsids formed by the Drosophila neuronal Arc proteins. Nature Neuroscience 23 (2), 172-175, Feb 2020